Search on: BIFUNCTIONAL REAGENTS 
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Descriptor English:   Cross-Linking Reagents 
Descriptor Spanish:   Reactivos de Enlaces Cruzados 
Descriptor Portuguese:   Reagentes para Ligações Cruzadas 
Synonyms English:   Bifunctional Reagents
Cross Linking Reagents
Crosslinking Reagents
Linking Reagents, Cross
Reagents, Bifunctional
Reagents, Cross Linking
Reagents, Cross-Linking
Reagents, Crosslinking  
Tree Number:   D27.720.470.410.210
Definition English:   Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other. 
History Note English:   80 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
Record Number:   3447 
Unique Identifier:   D003432 

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